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A Therapeutic Antibody against West Nile Virus Neutralizes Infection by Blocking Fusion within Endosomes

Defining the precise cellular mechanisms of neutralization by potently inhibitory antibodies is important for understanding how the immune system successfully limits viral infections. We recently described a potently inhibitory monoclonal antibody (MAb E16) against the envelope (E) protein of West N...

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Detalles Bibliográficos
Autores principales: Thompson, Bruce S., Moesker, Bastiaan, Smit, Jolanda M., Wilschut, Jan, Diamond, Michael S., Fremont, Daved H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679195/
https://www.ncbi.nlm.nih.gov/pubmed/19478866
http://dx.doi.org/10.1371/journal.ppat.1000453

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