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Mammalian microRNAs: a small world for fine-tuning gene expression

The basis of eukaryotic complexity is an intricate genetic architecture where parallel systems are involved in tuning gene expression, via RNA-DNA, RNA-RNA, RNA-protein, and DNA-protein interactions. In higher organisms, about 97% of the transcriptional output is represented by noncoding RNA (ncRNA)...

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Detalles Bibliográficos
Autores principales: Sevignani, Cinzia, Calin, George A., Siracusa, Linda D., Croce, Carlo M.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679635/
https://www.ncbi.nlm.nih.gov/pubmed/16518686
http://dx.doi.org/10.1007/s00335-005-0066-3