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The co-receptor signaling model of HIV-1 pathogenesis in peripheral CD4 T cells
HIV-mediated CD4 depletion is the hallmark of AIDS and is the most reliable predictor of disease progression. While HIV replication is associated with CD4 depletion in general, plasma viremia by itself predicts the rate of CD4 loss only minimally in untreated patients. To resolve this paradox, I hyp...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679705/ https://www.ncbi.nlm.nih.gov/pubmed/19409100 http://dx.doi.org/10.1186/1742-4690-6-41 |