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Germline-encoded amino acids in the αβ T cell receptor control thymic selection
An αβ T cell response depends on the recognition of antigen plus major histocompatibility complex proteins (MHC)1 by its antigen receptor (TCR). The ability of peripheral αβ T cells to recognize MHC is at least partly determined by MHC dependent thymic selection, by which an immature T cell survives...
Autores principales: | Scott-Browne, James P., White, Janice, Kappler, John W., Gapin, Laurent, Marrack, Philippa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679808/ https://www.ncbi.nlm.nih.gov/pubmed/19262510 http://dx.doi.org/10.1038/nature07812 |
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