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The Lysyl Oxidase Inhibitor, β-Aminopropionitrile, Diminishes the Metastatic Colonization Potential of Circulating Breast Cancer Cells
Lysyl oxidase (LOX), an extracellular matrix remodeling enzyme, appears to have a role in promoting breast cancer cell motility and invasiveness. In addition, increased LOX expression has been correlated with decreases in both metastases-free, and overall survival in breast cancer patients. With thi...
Autores principales: | Bondareva, Alla, Downey, Charlene M., Ayres, Fabio, Liu, Wei, Boyd, Steven K., Hallgrimsson, Benedikt, Jirik, Frank R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680032/ https://www.ncbi.nlm.nih.gov/pubmed/19440335 http://dx.doi.org/10.1371/journal.pone.0005620 |
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