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Characterization of a Novel Small Molecule Subtype Specific Estrogen-Related Receptor α Antagonist in MCF-7 Breast Cancer Cells

BACKGROUND: The orphan nuclear receptor estrogen-related receptor α (ERRα) is a member of the nuclear receptor superfamily. It was identified through a search for genes encoding proteins related to estrogen receptor α (ERα). An endogenous ligand has not been found. Novel ERRα antagonists that are hi...

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Detalles Bibliográficos
Autores principales: Chisamore, Michael J., Cunningham, Michael E., Flores, Osvaldo, Wilkinson, Hilary A., Chen, J. Don
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680043/
https://www.ncbi.nlm.nih.gov/pubmed/19462000
http://dx.doi.org/10.1371/journal.pone.0005624