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Sortase-mediated assembly and surface topology of adhesive pneumococcal pili

The rlrA genetic islet encodes an extracellular pilus in the Gram-positive pathogen Streptococcus pneumoniae. Of the three genes for structural subunits, rrgB encodes the major pilin, while rrgA and rrgC encode ancillary pilin subunits decorating the pilus shaft and tip. Deletion of all three pilus-...

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Detalles Bibliográficos
Autores principales: Fälker, Stefan, Nelson, Aaron L, Morfeldt, Eva, Jonas, Kristina, Hultenby, Kjell, Ries, Johannes, Melefors, Öjar, Normark, Staffan, Henriques-Normark, Birgitta
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680257/
https://www.ncbi.nlm.nih.gov/pubmed/18761697
http://dx.doi.org/10.1111/j.1365-2958.2008.06396.x

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