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Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms

BACKGROUND: The use of methotrexate is limited by interindividual variability in response. Previous studies in patients with either rheumatoid arthritis or psoriasis suggest that genetic variation across the methotrexate metabolic pathway might enable prediction of both efficacy and toxicity of the...

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Detalles Bibliográficos
Autores principales: Warren, RB, Smith, RL, Campalani, E, Eyre, S, Smith, CH, Barker, JNWN, Worthington, J, Griffiths, CEM
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680291/
https://www.ncbi.nlm.nih.gov/pubmed/19016697
http://dx.doi.org/10.1111/j.1365-2133.2008.08898.x

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