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Neo-Lymphoid Aggregates in the Adult Liver Can Initiate Potent Cell-Mediated Immunity
Subcutaneous immunization delivers antigen (Ag) to local Ag-presenting cells that subsequently migrate into draining lymph nodes (LNs). There, they initiate the activation and expansion of lymphocytes specific for their cognate Ag. In mammals, the structural environment of secondary lymphoid tissues...
Autores principales: | Greter, Melanie, Hofmann, Janin, Becher, Burkhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680335/ https://www.ncbi.nlm.nih.gov/pubmed/19468301 http://dx.doi.org/10.1371/journal.pbio.1000109 |
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