Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

Animal cells initiate cytokinesis in parallel with anaphase onset, when an actomyosin ring assembles and constricts through localized activation of the small GTPase RhoA, giving rise to a cleavage furrow. Furrow formation relies on positional cues provided by anaphase spindle microtubules (MTs), but...

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Detalles Bibliográficos
Autores principales: Burkard, Mark E., Maciejowski, John, Rodriguez-Bravo, Verónica, Repka, Michael, Lowery, Drew M., Clauser, Karl R., Zhang, Chao, Shokat, Kevan M., Carr, Steven A., Yaffe, Michael B., Jallepalli, Prasad V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680336/
https://www.ncbi.nlm.nih.gov/pubmed/19468302
http://dx.doi.org/10.1371/journal.pbio.1000111

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