Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

In this study, we demonstrate the suitability of the vertebrate Danio rerio (zebrafish) for functional screening of novel platelet genes in vivo by reverse genetics. Comparative transcript analysis of platelets and their precursor cell, the megakaryocyte, together with nucleated blood cell elements,...

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Detalles Bibliográficos
Autores principales: O'Connor, Marie N., Salles, Isabelle I., Cvejic, Ana, Watkins, Nicholas A., Walker, Adam, Garner, Stephen F., Jones, Chris I., Macaulay, Iain C., Steward, Michael, Zwaginga, Jaap-Jan, Bray, Sarah L., Dudbridge, Frank, de Bono, Bernard, Goodall, Alison H., Deckmyn, Hans, Stemple, Derek L., Ouwehand, Willem H.
Formato: Texto
Lenguaje:English
Publicado: American Society of Hematology 2009
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680375/
https://www.ncbi.nlm.nih.gov/pubmed/19109564
http://dx.doi.org/10.1182/blood-2008-06-162693

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