Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis H(37)R(v) and the β-Ketoacyl-ACP Synthase mtFabH

BACKGROUND: Tuberculosis (TB) is a disease which kills two million people every year and infects approximately over one-third of the world's population. The difficulty in managing tuberculosis is the prolonged treatment duration, the emergence of drug resistance and co-infection with HIV/AIDS....

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Detalles Bibliográficos
Autores principales: Al-Balas, Qosay, Anthony, Nahoum G., Al-Jaidi, Bilal, Alnimr, Amani, Abbott, Grainne, Brown, Alistair K., Taylor, Rebecca C., Besra, Gurdyal S., McHugh, Timothy D., Gillespie, Stephen H., Johnston, Blair F., Mackay, Simon P., Coxon, Geoffrey D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680598/
https://www.ncbi.nlm.nih.gov/pubmed/19440303
http://dx.doi.org/10.1371/journal.pone.0005617

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