Cargando…
Non-Invasive Molecular Imaging of Fibrosis Using a Collagen-Targeted Peptidomimetic of the Platelet Collagen Receptor Glycoprotein VI
BACKGROUND: Fibrosis, which is characterized by the pathological accumulation of collagen, is recognized as an important feature of many chronic diseases, and as such, constitutes an enormous health burden. We need non-invasive specific methods for the early diagnosis and follow-up of fibrosis in va...
Autores principales: | Muzard, Julien, Sarda-Mantel, Laure, Loyau, Stéphane, Meulemans, Alain, Louedec, Liliane, Bantsimba-Malanda, Claudie, Hervatin, Florence, Marchal-Somme, Joëlle, Michel, Jean Baptiste, Le Guludec, Dominique, Billiald, Philippe, Jandrot-Perrus, Martine |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680759/ https://www.ncbi.nlm.nih.gov/pubmed/19440310 http://dx.doi.org/10.1371/journal.pone.0005585 |
Ejemplares similares
-
Inhibition of Glycoprotein VI Clustering by Collagen as a Mechanism of Inhibiting Collagen-Induced Platelet Responses: The Example of Losartan
por: Jiang, Peng, et al.
Publicado: (2015) -
Collagen Can Selectively Trigger a Platelet Secretory Phenotype via Glycoprotein VI
por: Ollivier, Véronique, et al.
Publicado: (2014) -
Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of Collagen‐Induced Platelet Aggregation
por: Renaud, Lionel, et al.
Publicado: (2020) -
Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks
por: Lebozec, Kristell, et al.
Publicado: (2017) -
Glycoprotein VI in securing vascular integrity in inflamed vessels
por: Boulaftali, Yacine, et al.
Publicado: (2018)