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A mathematical model of aging-related and cortisol induced hippocampal dysfunction
BACKGROUND: The hippocampus is essential for declarative memory synthesis and is a core pathological substrate for Alzheimer's disease (AD), the most common aging-related dementing disease. Acute increases in plasma cortisol are associated with transient hippocampal inhibition and retrograde am...
Autores principales: | McAuley, Mark T, Kenny, Rose Anne, Kirkwood, Thomas BL, Wilkinson, Darren J, Jones, Janette JL, Miller, Veronica M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680862/ https://www.ncbi.nlm.nih.gov/pubmed/19320982 http://dx.doi.org/10.1186/1471-2202-10-26 |
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