Cargando…

Avicin D: A Protein Reactive Plant Isoprenoid Dephosphorylates Stat 3 by Regulating Both Kinase and Phosphatase Activities

Avicins, a class of electrophilic triterpenoids with pro-apoptotic, anti-inflammatory and antioxidant properties, have been shown to induce redox-dependant post-translational modification of cysteine residues to regulate protein function. Based on (a) the cross-talk that occurs between redox and pho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Haridas, Valsala, Nishimura, Goshi, Xu, Zhi-Xiang, Connolly, Fiona, Hanausek, Margaret, Walaszek, Zbigniew, Zoltaszek, Robert, Gutterman, Jordan U.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680980/ https://www.ncbi.nlm.nih.gov/pubmed/19440292 http://dx.doi.org/10.1371/journal.pone.0005578

Ejemplares similares

Avicin D, a Plant Triterpenoid, Induces Cell Apoptosis by Recruitment of Fas and Downstream Signaling Molecules into Lipid Rafts
por: Xu, Zhi-Xiang, et al.
Publicado: (2009)

The Anticancer Plant Triterpenoid, Avicin D, Regulates Glucocorticoid Receptor Signaling: Implications for Cellular Metabolism
por: Haridas, Valsala, et al.
Publicado: (2011)

Avicin G is a potent sphingomyelinase inhibitor and blocks oncogenic K- and H-Ras signaling
por: Garrido, Christian M., et al.
Publicado: (2020)

Enhancement of the productivity of the potent bacteriocin avicin A and improvement of its stability using nanotechnology approaches
por: Fahim, Hazem A., et al.
Publicado: (2017)

Effects of combined phytochemicals on skin tumorigenesis in SENCAR mice
por: KOWALCZYK, MAGDALENA C., et al.
Publicado: (2013)

Structural Basis of Response Regulator Dephosphorylation by Rap Phosphatases
por: Parashar, Vijay, et al.
Publicado: (2011)

The phosphohistidine phosphatase SixA dephosphorylates the phosphocarrier NPr
por: Schulte, Jane E., et al.
Publicado: (2020)

Protein tyrosine phosphatase receptor type D gene promotes radiosensitivity via STAT3 dephosphorylation in nasopharyngeal carcinoma
por: Lin, Yanling, et al.
Publicado: (2021)

Protein Phosphatase 1 Dephosphorylates Profilin-1 at Ser-137
por: Shao, Jieya, et al.
Publicado: (2012)

Protein Phosphatase-1α Interacts with and Dephosphorylates Polycystin-1
por: Parnell, Stephen C., et al.
Publicado: (2012)

Dephosphorylation of Centrins by Protein Phosphatase 2C α and β
por: Thissen, Marie-Christin, et al.
Publicado: (2009)

On-Slide Lambda Protein Phosphatase-Mediated Dephosphorylation of Fixed Samples
por: Tishchenko, Alexander, et al.
Publicado: (2023)

Dual-specificity phosphatase 23 mediates GCM1 dephosphorylation and activation
por: Lin, Fang-Yu, et al.
Publicado: (2011)

Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175
por: Ammosova, Tatiana, et al.
Publicado: (2011)

The phosphatase Shp1 interacts with and dephosphorylates cortactin to inhibit invadopodia function
por: Varone, Alessia, et al.
Publicado: (2021)

Protocol to assess substrate dephosphorylation by serine/threonine phosphoprotein phosphatases in vitro
por: Wasserman, Jason S., et al.
Publicado: (2023)

Metabolic engineering for the microbial production of isoprenoids: Carotenoids and isoprenoid-based biofuels
por: Niu, Fu-Xing, et al.
Publicado: (2017)

On the Origin of Isoprenoid Biosynthesis
por: Hoshino, Yosuke, et al.
Publicado: (2018)

Protein Tyrosine Phosphatases, TC-PTP, SHP1, and SHP2, Cooperate in Rapid Dephosphorylation of Stat3 in Keratinocytes Following UVB Irradiation
por: Kim, Dae Joon, et al.
Publicado: (2010)

Toxoplasma gondii Relies on Both Host and Parasite Isoprenoids and Can Be Rendered Sensitive to Atorvastatin
por: Li, Zhu-Hong, et al.
Publicado: (2013)

The control of inflammation via the phosphorylation and dephosphorylation of tristetraprolin: a tale of two phosphatases
por: Clark, Andrew R., et al.
Publicado: (2016)

Dephosphorylation of the Atg1 kinase complex by type 2C protein phosphatases
por: Memisoglu, Gonen, et al.
Publicado: (2019)

Protein phosphatase 4 promotes Hedgehog signaling through dephosphorylation of Suppressor of fused
por: Liao, Hengqing, et al.
Publicado: (2020)

Phosphatase Shp2 regulates biogenesis of small extracellular vesicles by dephosphorylating Syntenin
por: Zhang, Yuefei, et al.
Publicado: (2021)

Protein phosphatase 4 dephosphorylates phosphofructokinase-1 to regulate its enzymatic activity
por: Park, Jaehong, et al.
Publicado: (2023)

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription
por: Ammosova, Tatyana, et al.
Publicado: (2005)

Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T
por: Jideama, Nathan M., et al.
Publicado: (2006)

Role of Plastid Protein Phosphatase TAP38 in LHCII Dephosphorylation and Thylakoid Electron Flow
por: Pribil, Mathias, et al.
Publicado: (2010)

Vimentin dephosphorylation at ser-56 is regulated by type 1 protein phosphatase in smooth muscle
por: Li, Jia, et al.
Publicado: (2016)

STAT1 Gain-of-Function Mutations Cause High Total STAT1 Levels With Normal Dephosphorylation
por: Zimmerman, Ofer, et al.
Publicado: (2019)

Isoprenoid Alcohols are Susceptible to Oxidation with Singlet Oxygen and Hydroxyl Radicals
por: Komaszylo née Siedlecka, Joanna, et al.
Publicado: (2015)

Cell- and ligand-specific dephosphorylation of acid hydrolases: evidence that the mannose 6-phosphatase is controlled by compartmentalization
Publicado: (1991)

Protein phosphatase PP4: Role in dephosphorylation of KAP1 and DNA strand break repair
por: Pfeifer, Gerd P.
Publicado: (2012)

Dephosphorylation of DBC1 by Protein Phosphatase 4 Is Important for p53-Mediated Cellular Functions
por: Lee, Jihye, et al.
Publicado: (2015)

Nur1 Dephosphorylation Confers Positive Feedback to Mitotic Exit Phosphatase Activation in Budding Yeast
por: Godfrey, Molly, et al.
Publicado: (2015)

Structural and biochemical analysis of atypically low dephosphorylating activity of human dual-specificity phosphatase 28
por: Ku, Bonsu, et al.
Publicado: (2017)

MYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
por: Dingar, Dharmendra, et al.
Publicado: (2018)

Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A
por: Hoermann, Bernhard, et al.
Publicado: (2020)

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
por: Berndsen, Kerryn, et al.
Publicado: (2019)

Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1
por: Chen, Liping, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1dtov1bqaabcektbq0fc5oount