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Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status

We demonstrated previously that, in healthy young men, 5-aminoimidazole-4-carboxamide 1-β-d-ribofuranoside (AICAR) stimulates human muscle 2-deoxyglucose (2DG) uptake without detectable activation of muscle AMP-activated protein kinase (AMPK) but with extracellular-regulated kinase 1/2 (ERK1/2) acti...

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Detalles Bibliográficos
Autores principales:	Babraj, John Andree, Mustard, Kristy, Sutherland, Calum, Towler, Mhari C., Chen, Shaui, Smith, Kenneth, Green, Kevin, Leese, Graham, Hardie, David Grahame, Rennie, Michael J., Cuthbertson, Daniel James
Formato:	Texto
Lenguaje:	English
Publicado:	American Physiological Society 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681307/ https://www.ncbi.nlm.nih.gov/pubmed/19190259 http://dx.doi.org/10.1152/ajpendo.90811.2008

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