Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury

BACKGROUND: Phosphodiesterase-5 inhibition with sildenafil has been used to treat severe pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung disease in very preterm infants who were mechanically ventilated for respiratory distress syndrome. METHODS: Sildenafil treatment was i...

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Detalles Bibliográficos
Autores principales: de Visser, Yvonne P, Walther, Frans J, Laghmani, El Houari, Boersma, Hester, van der Laarse, Arnoud, Wagenaar, Gerry TM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681457/
https://www.ncbi.nlm.nih.gov/pubmed/19402887
http://dx.doi.org/10.1186/1465-9921-10-30

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