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Cdc7p-Dbf4p Regulates Mitotic Exit by Inhibiting Polo Kinase
Cdc7p-Dbf4p is a conserved protein kinase required for the initiation of DNA replication. The Dbf4p regulatory subunit binds Cdc7p and is essential for Cdc7p kinase activation, however, the N-terminal third of Dbf4p is dispensable for its essential replication activities. Here, we define a short N-t...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682205/ https://www.ncbi.nlm.nih.gov/pubmed/19478884 http://dx.doi.org/10.1371/journal.pgen.1000498 |