Synergy Disequilibrium Plots: graphical visualization of pairwise synergies and redundancies of SNPs with respect to a phenotype

Summary:We present a visualization tool applied on genome-wide association data, revealing disease-associated haplotypes, epistatically interacting loci, as well as providing visual signatures of multivariate correlations of genetic markers with respect to a phenotype. Availability:Freely available...

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Detalles Bibliográficos
Autores principales: Watkinson, John, Anastassiou, Dimitris
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682510/
https://www.ncbi.nlm.nih.gov/pubmed/19297347
http://dx.doi.org/10.1093/bioinformatics/btp159
Descripción
Sumario:Summary:We present a visualization tool applied on genome-wide association data, revealing disease-associated haplotypes, epistatically interacting loci, as well as providing visual signatures of multivariate correlations of genetic markers with respect to a phenotype. Availability:Freely available on the web at: http://www.ee.columbia.edu/~anastas/sdplots Contact:anastas@ee.columbia.edu Supplementary information: Supplementary data are available at Bioinformatics online.

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