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Reexamining microRNA Site Accessibility in Drosophila: A Population Genomics Study
Kertesz et al. (Nature Genetics 2008) described PITA, a miRNA target prediction algorithm based on hybridization energy and site accessibility. In this note, we used a population genomics approach to reexamine their data and found that the PITA algorithm had lower specificity than methods based on e...
Autores principales: | Chen, Kevin, Maaskola, Jonas, Siegal, Mark L., Rajewsky, Nikolaus |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682560/ https://www.ncbi.nlm.nih.gov/pubmed/19478854 http://dx.doi.org/10.1371/journal.pone.0005681 |
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