Cargando…

The Role of Toll-Like Receptor 2 in Inflammation and Fibrosis during Progressive Renal Injury

Tissue fibrosis and chronic inflammation are common causes of progressive organ damage, including progressive renal disease, leading to loss of physiological functions. Recently, it was shown that Toll-like receptor 2 (TLR2) is expressed in the kidney and activated by endogenous danger signals. The...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leemans, Jaklien C., Butter, Loes M., Pulskens, Wilco P. C., Teske, Gwendoline J. D., Claessen, Nike, van der Poll, Tom, Florquin, Sandrine
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682651/ https://www.ncbi.nlm.nih.gov/pubmed/19479087 http://dx.doi.org/10.1371/journal.pone.0005704

Ejemplares similares

Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury
por: Pulskens, Wilco P., et al.
Publicado: (2008)

Nlrp3 Prevents Early Renal Interstitial Edema and Vascular Permeability in Unilateral Ureteral Obstruction
por: Pulskens, Wilco P., et al.
Publicado: (2014)

Deficiency for the Chemokine Monocyte Chemoattractant Protein-1 Aggravates Tubular Damage after Renal Ischemia/Reperfusion Injury
por: Stroo, Ingrid, et al.
Publicado: (2015)

TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion
por: Bakker, Pieter J., et al.
Publicado: (2015)

Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease
por: Stroo, Ingrid, et al.
Publicado: (2012)

No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction
por: Stroo, Ingrid, et al.
Publicado: (2018)

S100A8/A9 Is Not Involved in Host Defense against Murine Urinary Tract Infection
por: Dessing, Mark C., et al.
Publicado: (2010)

Stem Cell Factor Expression after Renal Ischemia Promotes Tubular Epithelial Survival
por: Stokman, Geurt, et al.
Publicado: (2010)

CD44-Deficiency Attenuates the Immunologic Responses to LPS and Delays the Onset of Endotoxic Shock-Induced Renal Inflammation and Dysfunction
por: Rampanelli, Elena, et al.
Publicado: (2013)

Role of TREM1-DAP12 in Renal Inflammation during Obstructive Nephropathy
por: Tammaro, Alessandra, et al.
Publicado: (2013)

Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation
por: Tammaro, Alessandra, et al.
Publicado: (2016)

Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation
por: Tammaro, Alessandra, et al.
Publicado: (2017)

Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase
por: Stroo, Ingrid, et al.
Publicado: (2010)

Haematopoietic stem cell migration to the ischemic damaged kidney is not altered by manipulating the SDF-1/CXCR4-axis
por: Stroo, Ingrid, et al.
Publicado: (2009)

The dysregulation of metabolic pathways and induction of the pentose phosphate pathway in renal ischaemia–reperfusion injury
por: Scantlebery, Angelique ML, et al.
Publicado: (2021)

NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin
por: Scantlebery, Angelique M. L., et al.
Publicado: (2019)

TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells
por: Tammaro, Alessandra, et al.
Publicado: (2019)

Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection
por: Emal, Diba, et al.
Publicado: (2019)

Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation
por: Rampanelli, Elena, et al.
Publicado: (2017)

β-Cyclodextrin counteracts obesity in Western diet-fed mice but elicits a nephrotoxic effect
por: Scantlebery, Angelique M. L., et al.
Publicado: (2019)

NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity
por: Stokman, Geurt, et al.
Publicado: (2017)

Deletion of the Innate Immune NLRP3 Receptor Abolishes Cardiac Ischemic Preconditioning and Is Associated with Decreased Il-6/STAT3 Signaling
por: Zuurbier, Coert J., et al.
Publicado: (2012)

S100A8/A9 promotes parenchymal damage and renal fibrosis in obstructive nephropathy
por: Tammaro, A., et al.
Publicado: (2018)

Toll-like receptor 2 contributes to antibacterial defence against pneumolysin-deficient pneumococci
por: Dessing, Mark C, et al.
Publicado: (2008)

Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation
por: Dessing, Mark C., et al.
Publicado: (2015)

Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain
por: Uil, Melissa, et al.
Publicado: (2018)

Author Correction: Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the ‘resistant’ C57Bl/6J mouse strain
por: Uil, Melissa, et al.
Publicado: (2019)

Nicotine Protects Kidney from Renal Ischemia/Reperfusion Injury through the Cholinergic Anti-Inflammatory Pathway
por: Sadis, Claude, et al.
Publicado: (2007)

Toll-like receptor activation: from renal inflammation to fibrosis
por: Yiu, Wai Han, et al.
Publicado: (2014)

Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation
por: Dessing, Mark C., et al.
Publicado: (2016)

Renal and Urinary Levels of Endothelial Protein C Receptor Correlate with Acute Renal Allograft Rejection
por: Lattenist, Lionel, et al.
Publicado: (2013)

Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus
por: van der Sluijs, Koenraad F., et al.
Publicado: (2003)

Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis
por: Geldhoff, Madelijn, et al.
Publicado: (2013)

Role of Toll-Like Receptors 2 and 4 in Pulmonary Inflammation and Injury Induced by Pneumolysin in Mice
por: Dessing, Mark C., et al.
Publicado: (2009)

Toll-Like Receptor 2 Impairs Host Defense in Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis)
por: Wiersinga, W. Joost, et al.
Publicado: (2007)

Protease‐activated receptor‐1 contributes to renal injury and interstitial fibrosis during chronic obstructive nephropathy
por: Waasdorp, Maaike, et al.
Publicado: (2018)

The Azithromycin Pro-Drug CSY5669 Boosts Bacterial Killing While Attenuating Lung Inflammation Associated with Pneumonia Caused by Methicillin-Resistant Staphylococcus aureus
por: Saris, Anno, et al.
Publicado: (2022)

Toll-Like Receptor Signaling and SIGIRR in Renal Fibrosis upon Unilateral Ureteral Obstruction
por: Skuginna, Veronika, et al.
Publicado: (2011)

Early Activation of the Innate Immunity and Specific Cellular Immune Pathways after Vaccination with a Live Intranasal Viral Vaccine and Challenge with Bovine Parainfluenza Type 3 Virus
por: Nuijten, Piet, et al.
Publicado: (2022)

Limited Anti-Inflammatory Role for Interleukin-1 Receptor Like 1 (ST2) in the Host Response to Murine Postinfluenza Pneumococcal Pneumonia
por: Blok, Dana C., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8kkto5id0envp3gesk2coplt1q