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Apoptosis Is Essential for Neutrophil Functional Shutdown and Determines Tissue Damage in Experimental Pneumococcal Meningitis
During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages. Neutrophils show pro-inflammatory activity and may contribute to tissue damage. In pneumococcal meningitis, neuronal damag...
Autores principales: | Koedel, Uwe, Frankenberg, Tobias, Kirschnek, Susanne, Obermaier, Bianca, Häcker, Hans, Paul, Robert, Häcker, Georg |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682662/ https://www.ncbi.nlm.nih.gov/pubmed/19478887 http://dx.doi.org/10.1371/journal.ppat.1000461 |
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