Cargando…

Increased Risk of Type 2 Diabetes in Elderly Twins

OBJECTIVE: Genetic susceptibility, low birth weight (LBW), and aging are key etiological factors in the development of type 2 diabetes. LBW is common among twins. It is unknown whether twin status per se is associated with risk of type 2 diabetes, and valid concordance rates of type 2 diabetes in tw...

Descripción completa

Detalles Bibliográficos
Autores principales:	Poulsen, Pernille, Grunnet, Louise G., Pilgaard, Kasper, Storgaard, Heidi, Alibegovic, Amra, Sonne, Mette P., Carstensen, Bendix, Beck-Nielsen, Henning, Vaag, Allan
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2009
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682675/ https://www.ncbi.nlm.nih.gov/pubmed/19336677 http://dx.doi.org/10.2337/db08-1714

Ejemplares similares

Genetic versus Non-Genetic Regulation of miR-103, miR-143 and miR-483-3p Expression in Adipose Tissue and Their Metabolic Implications—A Twin Study
por: Bork-Jensen, Jette, et al.
Publicado: (2014)

Impact of Physical Inactivity on Adipose Tissue Low-Grade Inflammation in First-Degree Relatives of Type 2 Diabetic Patients
por: Højbjerre, Lise, et al.
Publicado: (2011)

Impact of 9 Days of Bed Rest on Hepatic and Peripheral Insulin Action, Insulin Secretion, and Whole-Body Lipolysis in Healthy Young Male Offspring of Patients With Type 2 Diabetes
por: Alibegovic, Amra C., et al.
Publicado: (2009)

Impact of Physical Inactivity on Subcutaneous Adipose Tissue Metabolism in Healthy Young Male Offspring of Patients With Type 2 Diabetes
por: Højbjerre, Lise, et al.
Publicado: (2010)

Leukocyte telomere length is associated with elevated plasma glucose and HbA1c in young healthy men independent of birth weight
por: Grunnet, L. G., et al.
Publicado: (2019)

Glucose tolerance is associated with differential expression of microRNAs in skeletal muscle: results from studies of twins with and without type 2 diabetes
por: Bork-Jensen, Jette, et al.
Publicado: (2014)

The T-Allele of TCF7L2 rs7903146 Associates With a Reduced Compensation of Insulin Secretion for Insulin Resistance Induced by 9 Days of Bed Rest
por: Alibegovic, Amra C., et al.
Publicado: (2010)

Retinol-Binding Protein 4 in Twins: Regulatory Mechanisms and Impact of Circulating and Tissue Expression Levels on Insulin Secretion and Action
por: Ribel-Madsen, Rasmus, et al.
Publicado: (2009)

Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue
por: Grunnet, Louise G., et al.
Publicado: (2009)

Genetic Variation in ATP5O Is Associated with Skeletal Muscle ATP50 mRNA Expression and Glucose Uptake in Young Twins
por: Rönn, Tina, et al.
Publicado: (2009)

Genome-Wide Analysis of DNA Methylation Differences in Muscle and Fat from Monozygotic Twins Discordant for Type 2 Diabetes
por: Ribel-Madsen, Rasmus, et al.
Publicado: (2012)

Do Gene Variants Influencing Adult Adiposity Affect Birth Weight? A Population-Based Study of 24 Loci in 4,744 Danish Individuals
por: Andersson, Ehm A., et al.
Publicado: (2010)

Associations between ambient air pollution and noise from road traffic with blood pressure and insulin resistance in children from Denmark
por: Pedersen, Marie, et al.
Publicado: (2019)

The Birth Weight Lowering C-Allele of rs900400 Near LEKR1 and CCNL1 Associates with Elevated Insulin Release following an Oral Glucose Challenge
por: Andersson, Ehm A., et al.
Publicado: (2011)

Relationship between insulin sensitivity and gene expression in human skeletal muscle
por: Parikh, Hemang M., et al.
Publicado: (2021)

Components of diabetes prevalence in Denmark 1996–2016 and future trends until 2030
por: Carstensen, Bendix, et al.
Publicado: (2020)

Prevalence, incidence and mortality of type 1 and type 2 diabetes in Denmark 1996–2016
por: Carstensen, Bendix, et al.
Publicado: (2020)

Lifetime risk and years lost to type 1 and type 2 diabetes in Denmark, 1996–2016
por: Carstensen, Bendix, et al.
Publicado: (2021)

MicroRNA Expression Signatures Determine Prognosis and Survival in Glioblastoma Multiforme—a Systematic Overview
por: Henriksen, Michael, et al.
Publicado: (2014)

Altered PI3-Kinase/Akt Signalling in Skeletal Muscle of Young Men with Low Birth Weight
por: Jensen, Christine B., et al.
Publicado: (2008)

Carboxylesterase 1 Gene Duplication and mRNA Expression in Adipose Tissue Are Linked to Obesity and Metabolic Function
por: Friedrichsen, Martin, et al.
Publicado: (2013)

Fish Intake in Pregnancy and Offspring Metabolic Parameters at Age 9–16—Does Gestational Diabetes Modify the Risk?
por: Maslova, Ekaterina, et al.
Publicado: (2018)

Abdominal visceral and subcutaneous adipose tissue and associations with cardiometabolic risk in Inuit, Africans and Europeans: a cross-sectional study
por: Rønn, Pernille Falberg, et al.
Publicado: (2020)

Effect of Adjunct Metformin Treatment in Patients with Type-1 Diabetes and Persistent Inadequate Glycaemic Control. A Randomized Study
por: Lund, Søren Søgaard, et al.
Publicado: (2008)

Influence of placental and peripheral malaria exposure in fetal life on cardiometabolic traits in adult offspring
por: Grunnet, Louise G, et al.
Publicado: (2022)

The Danish national type 2 diabetes cohort – the DD2 study
por: Sørensen, Henrik Toft, et al.
Publicado: (2012)

Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins
por: Soerensen, Mette, et al.
Publicado: (2022)

Spontaneous Septostomy in a Twin Pregnancy Causing Fatal Amniotic Band Syndrome
por: Hvelplund, Carolina, et al.
Publicado: (2018)

Cyclosporine and Extracorporeal Photopheresis are Equipotent in Treating Severe Atopic Dermatitis: A Randomized Cross-Over Study Comparing Two Efficient Treatment Modalities
por: Koppelhus, Uffe, et al.
Publicado: (2014)

The effect of insulin degludec on risk of symptomatic nocturnal hypoglycaemia in adults with type 1 diabetes and high risk of nocturnal severe hypoglycaemia (the HypoDeg trial): study rationale and design
por: Agesen, Rikke Mette, et al.
Publicado: (2019)

Skeletal muscle fibre type and enzymatic activity in adult offspring following placental and peripheral malaria exposure in foetal life
por: Christensen, Dirk L., et al.
Publicado: (2023)

The thrifty phenotype hypothesis revisited
por: Vaag, A. A., et al.
Publicado: (2012)

Low birthweight is associated with a higher incidence of type 2 diabetes over two decades independent of adult BMI and genetic predisposition
por: Wibaek, Rasmus, et al.
Publicado: (2023)

Birth Weight and Risk of Adiposity among Adult Inuit in Greenland
por: Rønn, Pernille Falberg, et al.
Publicado: (2014)

The Danish Centre for Strategic Research in Type 2 Diabetes (DD2) Project: rationale and planned nationwide studies of genetic predictors, physical exercise, and individualized pharmacological treatment
por: Steffensen, Charlotte, et al.
Publicado: (2012)

Communication and Social Relations: A Qualitative Study of Families’ Experience with Their Outpatient Pediatric Diabetes Visits
por: Jespersen, Louise Norman, et al.
Publicado: (2022)

Gene Expression in Skeletal Muscle Biopsies from People with Type 2 Diabetes and Relatives: Differential Regulation of Insulin Signaling Pathways
por: Palsgaard, Jane, et al.
Publicado: (2009)

Link Between GIP and Osteopontin in Adipose Tissue and Insulin Resistance
por: Ahlqvist, Emma, et al.
Publicado: (2013)

Carotid intima-media thickness in individuals with and without type 2 diabetes: a reproducibility study
por: Lundby-Christensen, Louise, et al.
Publicado: (2010)

Cytokines and Type 1 Diabetes: A Numbers Game
por: Grunnet, Lars Groth, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kghan9gn6h7n1tpko0n8t2gind