Cargando…
A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves
Methods based on genetic distance matrices usually lose information during the process of tree-building by converting a multi-dimensional matrix into a phylogenetic tree. We applied a heuristic method of two-dimensional presentation to achieve a better resolution of the relationship between breeds a...
Autores principales: | , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682822/ https://www.ncbi.nlm.nih.gov/pubmed/17612483 http://dx.doi.org/10.1186/1297-9686-39-4-447 |
_version_ | 1782167098850541568 |
---|---|
author | Veit-Kensch, Claudia E Medugorac, Ivica Jedrzejewski, Włodzimierz Bunevich, Aleksei N Foerster, Martin |
author_facet | Veit-Kensch, Claudia E Medugorac, Ivica Jedrzejewski, Włodzimierz Bunevich, Aleksei N Foerster, Martin |
author_sort | Veit-Kensch, Claudia E |
collection | PubMed |
description | Methods based on genetic distance matrices usually lose information during the process of tree-building by converting a multi-dimensional matrix into a phylogenetic tree. We applied a heuristic method of two-dimensional presentation to achieve a better resolution of the relationship between breeds and individuals investigated. Four hundred and nine individuals from nine German dog breed populations and one free-living wolf population were analysed with a marker set of 23 microsatellites. The result of the two-dimensional presentation was partly comparable with and complemented a model-based analysis that uses genotype patterns. The assignment test and the neighbour-joining tree based on allele sharing estimate allocated 99% and 97% of the individuals according to their breed, respectively. The application of the two-dimensional presentation to distances on the basis of the proportion of shared alleles resulted in comparable and further complementary insight into inferred population structure by multilocus genotype data. We expect that the inference of population structure in domesticated species with complex breeding histories can be strongly supported by the two-dimensional presentation based on the described heuristic method. |
format | Text |
id | pubmed-2682822 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-26828222009-05-16 A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves Veit-Kensch, Claudia E Medugorac, Ivica Jedrzejewski, Włodzimierz Bunevich, Aleksei N Foerster, Martin Genet Sel Evol Research Methods based on genetic distance matrices usually lose information during the process of tree-building by converting a multi-dimensional matrix into a phylogenetic tree. We applied a heuristic method of two-dimensional presentation to achieve a better resolution of the relationship between breeds and individuals investigated. Four hundred and nine individuals from nine German dog breed populations and one free-living wolf population were analysed with a marker set of 23 microsatellites. The result of the two-dimensional presentation was partly comparable with and complemented a model-based analysis that uses genotype patterns. The assignment test and the neighbour-joining tree based on allele sharing estimate allocated 99% and 97% of the individuals according to their breed, respectively. The application of the two-dimensional presentation to distances on the basis of the proportion of shared alleles resulted in comparable and further complementary insight into inferred population structure by multilocus genotype data. We expect that the inference of population structure in domesticated species with complex breeding histories can be strongly supported by the two-dimensional presentation based on the described heuristic method. BioMed Central 2007-07-06 /pmc/articles/PMC2682822/ /pubmed/17612483 http://dx.doi.org/10.1186/1297-9686-39-4-447 Text en Copyright © 2007 INRA, EDP Sciences |
spellingShingle | Research Veit-Kensch, Claudia E Medugorac, Ivica Jedrzejewski, Włodzimierz Bunevich, Aleksei N Foerster, Martin A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves |
title | A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves |
title_full | A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves |
title_fullStr | A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves |
title_full_unstemmed | A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves |
title_short | A heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves |
title_sort | heuristic two-dimensional presentation of microsatellite-based data applied to dogs and wolves |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682822/ https://www.ncbi.nlm.nih.gov/pubmed/17612483 http://dx.doi.org/10.1186/1297-9686-39-4-447 |
work_keys_str_mv | AT veitkenschclaudiae aheuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT medugoracivica aheuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT jedrzejewskiwłodzimierz aheuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT bunevichaleksein aheuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT foerstermartin aheuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT veitkenschclaudiae heuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT medugoracivica heuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT jedrzejewskiwłodzimierz heuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT bunevichaleksein heuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves AT foerstermartin heuristictwodimensionalpresentationofmicrosatellitebaseddataappliedtodogsandwolves |