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Advances in pharmacological strategies for the prevention of cataract development
Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683438/ https://www.ncbi.nlm.nih.gov/pubmed/19384010 http://dx.doi.org/10.4103/0301-4738.49390 |
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author | Gupta, S K Selvan, V Kalai Agrawal, S S Saxena, Rohit |
author_facet | Gupta, S K Selvan, V Kalai Agrawal, S S Saxena, Rohit |
author_sort | Gupta, S K |
collection | PubMed |
description | Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of putative anticataract agents comes from a variety of approaches, ranging from laboratory experiments, both in vitro and in vivo, to epidemiological studies in patients. This review deals with the various mechanisms, and possible pharmacological interventions for the prevention of cataract. The article also reviews research on potential anticataractous agents, including aldose reductase inhibitors, glutathione boosters, antiglycating agents, vitamins and various drugs from indigenous sources. |
format | Text |
id | pubmed-2683438 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-26834382009-05-27 Advances in pharmacological strategies for the prevention of cataract development Gupta, S K Selvan, V Kalai Agrawal, S S Saxena, Rohit Indian J Ophthalmol Review Article Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of putative anticataract agents comes from a variety of approaches, ranging from laboratory experiments, both in vitro and in vivo, to epidemiological studies in patients. This review deals with the various mechanisms, and possible pharmacological interventions for the prevention of cataract. The article also reviews research on potential anticataractous agents, including aldose reductase inhibitors, glutathione boosters, antiglycating agents, vitamins and various drugs from indigenous sources. Medknow Publications 2009 /pmc/articles/PMC2683438/ /pubmed/19384010 http://dx.doi.org/10.4103/0301-4738.49390 Text en © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Gupta, S K Selvan, V Kalai Agrawal, S S Saxena, Rohit Advances in pharmacological strategies for the prevention of cataract development |
title | Advances in pharmacological strategies for the prevention of cataract development |
title_full | Advances in pharmacological strategies for the prevention of cataract development |
title_fullStr | Advances in pharmacological strategies for the prevention of cataract development |
title_full_unstemmed | Advances in pharmacological strategies for the prevention of cataract development |
title_short | Advances in pharmacological strategies for the prevention of cataract development |
title_sort | advances in pharmacological strategies for the prevention of cataract development |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683438/ https://www.ncbi.nlm.nih.gov/pubmed/19384010 http://dx.doi.org/10.4103/0301-4738.49390 |
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