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Advances in pharmacological strategies for the prevention of cataract development

Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of...

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Detalles Bibliográficos
Autores principales: Gupta, S K, Selvan, V Kalai, Agrawal, S S, Saxena, Rohit
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683438/
https://www.ncbi.nlm.nih.gov/pubmed/19384010
http://dx.doi.org/10.4103/0301-4738.49390
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author Gupta, S K
Selvan, V Kalai
Agrawal, S S
Saxena, Rohit
author_facet Gupta, S K
Selvan, V Kalai
Agrawal, S S
Saxena, Rohit
author_sort Gupta, S K
collection PubMed
description Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of putative anticataract agents comes from a variety of approaches, ranging from laboratory experiments, both in vitro and in vivo, to epidemiological studies in patients. This review deals with the various mechanisms, and possible pharmacological interventions for the prevention of cataract. The article also reviews research on potential anticataractous agents, including aldose reductase inhibitors, glutathione boosters, antiglycating agents, vitamins and various drugs from indigenous sources.
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spelling pubmed-26834382009-05-27 Advances in pharmacological strategies for the prevention of cataract development Gupta, S K Selvan, V Kalai Agrawal, S S Saxena, Rohit Indian J Ophthalmol Review Article Cataractous-opacification of the lens is one of the leading causes of blindness in India. The situation can be managed by surgical removal of the cataractous lens. Various pharmacological strategies have been proposed for the prevention and treatment of cataract. Information on possible benefits of putative anticataract agents comes from a variety of approaches, ranging from laboratory experiments, both in vitro and in vivo, to epidemiological studies in patients. This review deals with the various mechanisms, and possible pharmacological interventions for the prevention of cataract. The article also reviews research on potential anticataractous agents, including aldose reductase inhibitors, glutathione boosters, antiglycating agents, vitamins and various drugs from indigenous sources. Medknow Publications 2009 /pmc/articles/PMC2683438/ /pubmed/19384010 http://dx.doi.org/10.4103/0301-4738.49390 Text en © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Gupta, S K
Selvan, V Kalai
Agrawal, S S
Saxena, Rohit
Advances in pharmacological strategies for the prevention of cataract development
title Advances in pharmacological strategies for the prevention of cataract development
title_full Advances in pharmacological strategies for the prevention of cataract development
title_fullStr Advances in pharmacological strategies for the prevention of cataract development
title_full_unstemmed Advances in pharmacological strategies for the prevention of cataract development
title_short Advances in pharmacological strategies for the prevention of cataract development
title_sort advances in pharmacological strategies for the prevention of cataract development
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683438/
https://www.ncbi.nlm.nih.gov/pubmed/19384010
http://dx.doi.org/10.4103/0301-4738.49390
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