Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1

PTEN-induced novel kinase 1 (PINK1) mutations are associated with autosomal recessive parkinsonism. Previous studies have shown that PINK1 influences both mitochondrial function and morphology although it is not clearly established which of these are primary events and which are secondary. Here, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Sandebring, Anna, Thomas, Kelly Jean, Beilina, Alexandra, van der Brug, Marcel, Cleland, Megan M., Ahmad, Rili, Miller, David W., Zambrano, Ibardo, Cowburn, Richard F., Behbahani, Homira, Cedazo-Mínguez, Angel, Cookson, Mark R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683574/
https://www.ncbi.nlm.nih.gov/pubmed/19492085
http://dx.doi.org/10.1371/journal.pone.0005701

Ejemplares similares

Ejemplares similares