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Efficient protein depletion by genetically controlled deprotection of a dormant N-degron
Methods that allow for the manipulation of genes or their products have been highly fruitful for biomedical research. Here, we describe a method that allows the control of protein abundance by a genetically encoded regulatory system. We developed a dormant N-degron that can be attached to the N-term...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683728/ https://www.ncbi.nlm.nih.gov/pubmed/19401679 http://dx.doi.org/10.1038/msb.2009.25 |