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Src, PKCα, and PKCδ are required for αvβ3 integrin-mediated metastatic melanoma invasion
BACKGROUND: Integrins, cell-surface receptors that mediate adhesive interactions between cells and the extracellular matrix (ECM), play an important role in cancer progression. Expression of the vitronectin receptor αvβ3 integrin correlates with increased invasive and metastatic capacity of malignan...
Autores principales: | Putnam, Andrew J, Schulz, Veronique V, Freiter, Eric M, Bill, Heather M, Miranti, Cindy K |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683837/ https://www.ncbi.nlm.nih.gov/pubmed/19400942 http://dx.doi.org/10.1186/1478-811X-7-10 |
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