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Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa

BACKGROUND: Hospital Acquired Urinary Tract Infection (HAUTI) is the commonest among the nosocomial infections, and hospital specific data concerning its magnitude and attributes is essential to its effective control. MATERIALS AND METHODS: Prospective study was undertaken among 498 in-patients at t...

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Autores principales: Kamat, Umesh S., Fereirra, Agnelo, Amonkar, Dilip, Motghare, Dilip D., Kulkarni, Manoj S.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684314/
https://www.ncbi.nlm.nih.gov/pubmed/19468434
http://dx.doi.org/10.4103/0970-1591.45542
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author Kamat, Umesh S.
Fereirra, Agnelo
Amonkar, Dilip
Motghare, Dilip D.
Kulkarni, Manoj S.
author_facet Kamat, Umesh S.
Fereirra, Agnelo
Amonkar, Dilip
Motghare, Dilip D.
Kulkarni, Manoj S.
author_sort Kamat, Umesh S.
collection PubMed
description BACKGROUND: Hospital Acquired Urinary Tract Infection (HAUTI) is the commonest among the nosocomial infections, and hospital specific data concerning its magnitude and attributes is essential to its effective control. MATERIALS AND METHODS: Prospective study was undertaken among 498 in-patients at the medical college hospital in Goa, employing the clinico-bacteriologic criteria of CDC, Atlanta, in the representative medicine and surgery wards. Antimicrobial sensitivity was tested using the Kirby-Bauer disc diffusion method. STATISTICAL ANALYSIS: Statistical significance of association was tested using the chi-square test and the unpaired t-test at 5% level of significance, while the strength of association was expressed as the Odd's ratio with 95% confidence interval calculated by Wolff's method. RESULTS: While the overall infection rate was 8.03/100 admissions, 33.6% of the catheterized patients developed HAUTI. Effect of gender was found to remain restricted to the development of HAUTI among females at an earlier age and earlier in time series compared to males, but no overall difference in incidence in the two sexes. The factors significantly associated with HAUTI included: duration of hospitalization, per urethral catheterization and the duration of catheterization. E. coli, Pseudomonas, Kebsiella, and Candida accounted for over 90% of the isolates, and 73.5% of these were resistant to all the antibiotics for which sensitivity was tested. The remaining isolates demonstrated sensitivity to amikacin and/or cefoperazone-sulbactam. CONCLUSION: High infection rate coupled with widespread isolation polyantimicrobial resistant nosocomial pathogens emphasizes the importance of meticulous surveillance of nosocomial infections in the hospital, with due attention to antibiotic prescription practices.
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spelling pubmed-26843142009-05-22 Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa Kamat, Umesh S. Fereirra, Agnelo Amonkar, Dilip Motghare, Dilip D. Kulkarni, Manoj S. Indian J Urol Original Article BACKGROUND: Hospital Acquired Urinary Tract Infection (HAUTI) is the commonest among the nosocomial infections, and hospital specific data concerning its magnitude and attributes is essential to its effective control. MATERIALS AND METHODS: Prospective study was undertaken among 498 in-patients at the medical college hospital in Goa, employing the clinico-bacteriologic criteria of CDC, Atlanta, in the representative medicine and surgery wards. Antimicrobial sensitivity was tested using the Kirby-Bauer disc diffusion method. STATISTICAL ANALYSIS: Statistical significance of association was tested using the chi-square test and the unpaired t-test at 5% level of significance, while the strength of association was expressed as the Odd's ratio with 95% confidence interval calculated by Wolff's method. RESULTS: While the overall infection rate was 8.03/100 admissions, 33.6% of the catheterized patients developed HAUTI. Effect of gender was found to remain restricted to the development of HAUTI among females at an earlier age and earlier in time series compared to males, but no overall difference in incidence in the two sexes. The factors significantly associated with HAUTI included: duration of hospitalization, per urethral catheterization and the duration of catheterization. E. coli, Pseudomonas, Kebsiella, and Candida accounted for over 90% of the isolates, and 73.5% of these were resistant to all the antibiotics for which sensitivity was tested. The remaining isolates demonstrated sensitivity to amikacin and/or cefoperazone-sulbactam. CONCLUSION: High infection rate coupled with widespread isolation polyantimicrobial resistant nosocomial pathogens emphasizes the importance of meticulous surveillance of nosocomial infections in the hospital, with due attention to antibiotic prescription practices. Medknow Publications 2009 /pmc/articles/PMC2684314/ /pubmed/19468434 http://dx.doi.org/10.4103/0970-1591.45542 Text en © Indian Journal of Urology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kamat, Umesh S.
Fereirra, Agnelo
Amonkar, Dilip
Motghare, Dilip D.
Kulkarni, Manoj S.
Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa
title Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa
title_full Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa
title_fullStr Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa
title_full_unstemmed Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa
title_short Epidemiology of hospital acquired urinary tract infections in a medical college hospital in Goa
title_sort epidemiology of hospital acquired urinary tract infections in a medical college hospital in goa
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684314/
https://www.ncbi.nlm.nih.gov/pubmed/19468434
http://dx.doi.org/10.4103/0970-1591.45542
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