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Analysis of 7,8-Dihydro-8-oxo-2′-deoxyguanosine in Cellular DNA during Oxidative Stress

[Image: see text] Analysis of cellular 7,8-dihydro-8-oxo-2′-deoxyguanosine (8-oxo-dGuo) as a biomarker of oxidative DNA damage has been fraught with numerous methodological problems. This is primarily due to artifactual oxidation of dGuo that occurs during DNA isolation and hydrolysis. Therefore, it...

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Detalles Bibliográficos
Autores principales:	Mangal, Dipti, Vudathala, Daljit, Park, Jong-Heum, Lee, Seon Hwa, Penning, Trevor M., Blair, Ian A.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2009
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684441/ https://www.ncbi.nlm.nih.gov/pubmed/19309085 http://dx.doi.org/10.1021/tx800343c

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