REUL Is a Novel E3 Ubiquitin Ligase and Stimulator of Retinoic-Acid-Inducible Gene-I

RIG-I and MDA5 are cytoplasmic sensors that recognize different species of viral RNAs, leads to activation of the transcription factors IRF3 and NF-κB, which collaborate to induce type I interferons. In this study, we identified REUL, a RING-finger protein, as a specific RIG-I-interacting protein. R...

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Detalles Bibliográficos
Autores principales: Gao, Dong, Yang, Yong-Kang, Wang, Rui-Peng, Zhou, Xiang, Diao, Fei-Ci, Li, Min-Dian, Zhai, Zhong-He, Jiang, Zheng-Fan, Chen, Dan-Ying
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684588/
https://www.ncbi.nlm.nih.gov/pubmed/19484123
http://dx.doi.org/10.1371/journal.pone.0005760

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