High Mutability of the Tumor Suppressor Genes RASSF1 and RBSP3 (CTDSPL) in Cancer

BACKGROUND: Many different genetic alterations are observed in cancer cells. Individual cancer genes display point mutations such as base changes, insertions and deletions that initiate and promote cancer growth and spread. Somatic hypermutation is a powerful mechanism for generation of different mu...

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Detalles Bibliográficos
Autores principales: Kashuba, Vladimir I., Pavlova, Tatiana V., Grigorieva, Elvira V., Kutsenko, Alexey, Yenamandra, Surya Pavan, Li, Jingfeng, Wang, Fuli, Protopopov, Alexei I., Zabarovska, Veronika I., Senchenko, Vera, Haraldson, Klas, Eshchenko, Tatiana, Kobliakova, Julia, Vorontsova, Olga, Kuzmin, Igor, Braga, Eleonora, Blinov, Vladimir M., Kisselev, Lev L., Zeng, Yi-Xin, Ernberg, Ingemar, Lerman, Michael I., Klein, George, Zabarovsky, Eugene R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684631/
https://www.ncbi.nlm.nih.gov/pubmed/19478941
http://dx.doi.org/10.1371/journal.pone.0005231

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