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Prion Strain Discrimination Based on Rapid In Vivo Amplification and Analysis by the Cell Panel Assay
Prion strain identification has been hitherto achieved using time-consuming incubation time determinations in one or more mouse lines and elaborate neuropathological assessment. In the present work, we make a detailed study of the properties of PrP-overproducing Tga20 mice. We show that in these mic...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684634/ https://www.ncbi.nlm.nih.gov/pubmed/19478942 http://dx.doi.org/10.1371/journal.pone.0005730 |