Control Design for Signal Transduction Networks

Signal transduction networks of biological systems are highly complex. How to mathematically describe a signal transduction network by systematic approaches to further develop an appropriate and effective control strategy is attractive to control engineers. In this paper, the synergism and saturatio...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Liang, Liu, Yuan-Wei, Chuang, Chia-Hua
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684693/
https://www.ncbi.nlm.nih.gov/pubmed/20072602
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author Lin, Chun-Liang
Liu, Yuan-Wei
Chuang, Chia-Hua
author_facet Lin, Chun-Liang
Liu, Yuan-Wei
Chuang, Chia-Hua
author_sort Lin, Chun-Liang
collection PubMed
description Signal transduction networks of biological systems are highly complex. How to mathematically describe a signal transduction network by systematic approaches to further develop an appropriate and effective control strategy is attractive to control engineers. In this paper, the synergism and saturation system (S-systems) representations are used to describe signal transduction networks and a control design idea is presented. For constructing mathematical models, a cascaded analysis model is first proposed. Dynamic analysis and controller design are simulated and verified.
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spelling pubmed-26846932010-01-21 Control Design for Signal Transduction Networks Lin, Chun-Liang Liu, Yuan-Wei Chuang, Chia-Hua Bioinform Biol Insights Original Research Signal transduction networks of biological systems are highly complex. How to mathematically describe a signal transduction network by systematic approaches to further develop an appropriate and effective control strategy is attractive to control engineers. In this paper, the synergism and saturation system (S-systems) representations are used to describe signal transduction networks and a control design idea is presented. For constructing mathematical models, a cascaded analysis model is first proposed. Dynamic analysis and controller design are simulated and verified. Libertas Academica 2009-02-09 /pmc/articles/PMC2684693/ /pubmed/20072602 Text en Copyright © 2009 The authors. http://creativecommons.org/licenses/by/2.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/2.0/).
spellingShingle Original Research
Lin, Chun-Liang
Liu, Yuan-Wei
Chuang, Chia-Hua
Control Design for Signal Transduction Networks
title Control Design for Signal Transduction Networks
title_full Control Design for Signal Transduction Networks
title_fullStr Control Design for Signal Transduction Networks
title_full_unstemmed Control Design for Signal Transduction Networks
title_short Control Design for Signal Transduction Networks
title_sort control design for signal transduction networks
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684693/
https://www.ncbi.nlm.nih.gov/pubmed/20072602
work_keys_str_mv AT linchunliang controldesignforsignaltransductionnetworks
AT liuyuanwei controldesignforsignaltransductionnetworks
AT chuangchiahua controldesignforsignaltransductionnetworks

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