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Sonic hedgehog: its expression in a healing cornea and its role in neovascularization
PURPOSE: To examine if sonic hedgehog (Shh) is involved in tissue neovascularization by using cell culture and an animal cornea. METHODS: The effects of exogenous Shh (5.0 nM), vascular endothelial growth factor (VEGF), and/or a Shh signal inhibitor (2.5 or 10.0 μM cyclopamine) on vessel-like tube f...
Autores principales: | Fujita, Kyoko, Miyamoto, Takeshi, Saika, Shizuya |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684749/ https://www.ncbi.nlm.nih.gov/pubmed/19471603 |
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