Phenotypic Characterization of Autoreactive B Cells—Checkpoints of B Cell Tolerance in Patients with Systemic Lupus Erythematosus

DNA-reactive B cells play a central role in systemic lupus erythematosus (SLE); DNA antibodies precede clinical disease and in established disease correlate with renal inflammation and contribute to dendritic cell activation and high levels of type 1 interferon. A number of central and peripheral B...

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Detalles Bibliográficos
Autores principales: Jacobi, Annett M., Zhang, Jie, Mackay, Meggan, Aranow, Cynthia, Diamond, Betty
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685013/
https://www.ncbi.nlm.nih.gov/pubmed/19488401
http://dx.doi.org/10.1371/journal.pone.0005776

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