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The poly dA helix: a new structural motif for high performance DNA-based molecular switches

We report a pH-dependent conformational transition in short, defined homopolymeric deoxyadenosines (dA(15)) from a single helical structure with stacked nucleobases at neutral pH to a double-helical, parallel-stranded duplex held together by AH(+)-H(+)A base pairs at acidic pH. Using native PAGE, 2D...

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Detalles Bibliográficos
Autores principales:	Chakraborty, Saikat, Sharma, Suruchi, Maiti, Prabal K., Krishnan, Yamuna
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685084/ https://www.ncbi.nlm.nih.gov/pubmed/19279188 http://dx.doi.org/10.1093/nar/gkp133

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