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Silencing by nuclear matrix attachment distinguishes cell-type specificity: association with increased proliferation capacity
DNA loop organization by nuclear scaffold/matrix attachment is a key regulator of gene expression that may provide a means to modulate phenotype. We have previously shown that attachment of genes to the NaCl-isolated nuclear matrix correlates with their silencing in HeLa cells. In contrast, expresse...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685086/ https://www.ncbi.nlm.nih.gov/pubmed/19276204 http://dx.doi.org/10.1093/nar/gkp135 |