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The universal YrdC/Sua5 family is required for the formation of threonylcarbamoyladenosine in tRNA
Threonylcarbamoyladenosine (t(6)A) is a universal modification found at position 37 of ANN decoding tRNAs, which imparts a unique structure to the anticodon loop enhancing its binding to ribosomes in vitro. Using a combination of bioinformatic, genetic, structural and biochemical approaches, the uni...
Autores principales: | El Yacoubi, Basma, Lyons, Benjamin, Cruz, Yulien, Reddy, Robert, Nordin, Brian, Agnelli, Fabio, Williamson, James R., Schimmel, Paul, Swairjo, Manal A., de Crécy-Lagard, Valérie |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685093/ https://www.ncbi.nlm.nih.gov/pubmed/19287007 http://dx.doi.org/10.1093/nar/gkp152 |
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