Cargando…

Structural basis of tRNA modification with CO(2) fixation and methylation by wybutosine synthesizing enzyme TYW4

Wybutosine (yW), one of the most complicated modified nucleosides, is found in the anticodon loop of eukaryotic phenylalanine tRNA. This hypermodified nucleoside ensures correct codon recognition by stabilizing codon-anticodon pairings during the decoding process in the ribosome. TYW4 is an S-adenos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Suzuki, Yoko, Noma, Akiko, Suzuki, Tsutomu, Ishitani, Ryuichiro, Nureki, Osamu
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685095/ https://www.ncbi.nlm.nih.gov/pubmed/19287006 http://dx.doi.org/10.1093/nar/gkp158

Ejemplares similares

Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification
por: Kato, Megumi, et al.
Publicado: (2011)

Structure-Function Analysis of Human TYW2 Enzyme Required for the Biosynthesis of a Highly Modified Wybutosine (yW) Base in Phenylalanine-tRNA
por: Rodriguez, Virginia, et al.
Publicado: (2012)

Structural basis for translation termination by archaeal RF1 and GTP-bound EF1α complex
por: Kobayashi, Kan, et al.
Publicado: (2012)

Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNA(Gln) formation
por: Nureki, Osamu, et al.
Publicado: (2010)

Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm
por: Nozawa, Kayo, et al.
Publicado: (2013)

Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases
por: Araiso, Yuhei, et al.
Publicado: (2014)

Pyrrolysyl-tRNA synthetase:tRNA(Pyl) structure reveals the molecular basis of orthogonality
por: Nozawa, Kayo, et al.
Publicado: (2008)

Structural basis for the selective methylation of 5-carboxymethoxyuridine in tRNA modification
por: Yoo, Jaehun, et al.
Publicado: (2023)

The non-canonical hydroxylase structure of YfcM reveals a metal ion-coordination motif required for EF-P hydroxylation
por: Kobayashi, Kan, et al.
Publicado: (2014)

Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter
por: Lee, Yongchan, et al.
Publicado: (2015)

C-terminal domain of archaeal O-phosphoseryl-tRNA kinase displays large-scale motion to bind the 7-bp D-stem of archaeal tRNA(Sec)
por: Sherrer, R. Lynn, et al.
Publicado: (2011)

Structural insights into RNA-dependent eukaryal and archaeal selenocysteine formation
por: Araiso, Yuhei, et al.
Publicado: (2008)

Role of Wybutosine and Mg(2+) Ions in Modulating the Structure and Function of tRNA(Phe): A Molecular Dynamics Study
por: Fandilolu, Prayagraj M., et al.
Publicado: (2019)

Structural basis for recognition of G-1-containing tRNA by histidyl-tRNA synthetase
por: Tian, Qingnan, et al.
Publicado: (2015)

Crystallization and preliminary X-ray crystallographic analysis of YfcM: an important factor for EF-P hydroxylation
por: Kobayashi, Kan, et al.
Publicado: (2014)

Structural basis for recognition of cognate tRNA by tyrosyl-tRNA synthetase from three kingdoms
por: Tsunoda, Masaru, et al.
Publicado: (2007)

Structural basis for the dynamics of human methionyl-tRNA synthetase in multi-tRNA synthetase complexes
por: Kim, Dong Kyu, et al.
Publicado: (2021)

Structural and functional characterization of the TYW3/Taw3 class of SAM-dependent methyltransferases
por: Currie, Mark A., et al.
Publicado: (2017)

Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase
por: Yu, Zhaoli, et al.
Publicado: (2023)

Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer
por: Rosselló-Tortella, Margalida, et al.
Publicado: (2020)

Mechanistic characterization of the sulfur-relay system for eukaryotic 2-thiouridine biogenesis at tRNA wobble positions
por: Noma, Akiko, et al.
Publicado: (2009)

Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase
por: Ito, Kosuke, et al.
Publicado: (2012)

Recent structural studies on Dom34/aPelota and Hbs1/aEF1α: important factors for solving general problems of ribosomal stall in translation
por: Kobayashi, Kan, et al.
Publicado: (2013)

Structural basis for oligomerization of the prokaryotic peptide transporter PepT(So2)
por: Nagamura, Reina, et al.
Publicado: (2019)

Functional roles of Mg(2+) binding sites in ion-dependent gating of a Mg(2+) channel, MgtE, revealed by solution NMR
por: Maruyama, Tatsuro, et al.
Publicado: (2018)

Origin and evolution of peptide-modifying dioxygenases and identification of the wybutosine hydroxylase/hydroperoxidase
por: Iyer, Lakshminarayan M., et al.
Publicado: (2010)

Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans
por: Puppala, Anupama K, et al.
Publicado: (2023)

Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
por: Fukuda, Masahiro, et al.
Publicado: (2015)

Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9
por: Hirano, Seiichi, et al.
Publicado: (2019)

Molecular basis of cobalamin-dependent RNA modification
por: Dowling, Daniel P., et al.
Publicado: (2016)

Identification of a novel 5-aminomethyl-2-thiouridine methyltransferase in tRNA modification
por: Cho, Gyuhyeok, et al.
Publicado: (2023)

Eukaryotic TYW1 Is a Radical SAM Flavoenzyme
por: Young, Anthony P., et al.
Publicado: (2021)

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification
por: Thomas, Sherine E, et al.
Publicado: (2020)

Structural basis of transcription regulation by CNC family transcription factor, Nrf2
por: Sengoku, Toru, et al.
Publicado: (2022)

RNA modifications stabilize the tertiary structure of tRNA(fMet) by locally increasing conformational dynamics
por: Biedenbänder, Thomas, et al.
Publicado: (2022)

Lateral access mechanism of LPA receptor probed by molecular dynamics simulation
por: Suenaga, Rieko, et al.
Publicado: (2022)

Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg(2+) channel MgtE
por: Takeda, Hironori, et al.
Publicado: (2014)

The RNA acetyltransferase driven by ATP hydrolysis synthesizes N(4)-acetylcytidine of tRNA anticodon
por: Ikeuchi, Yoshiho, et al.
Publicado: (2008)

Structural basis for sequence-dependent recognition of colicin E5 tRNase by mimicking the mRNA–tRNA interaction
por: Yajima, Shunsuke, et al.
Publicado: (2006)

Structural basis of yeast aminoacyl-tRNA synthetase complex formation revealed by crystal structures of two binary sub-complexes
por: Simader, Hannes, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_1h6jk0fk3m0gfqf7j76r39jd9u