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Creation of the two isoforms of rodent NKG2D was driven by a B1 retrotransposon insertion
The mouse gene for the natural killer (NK) cell-activating receptor Nkg2d produces two protein isoforms, NKG2D-S and NKG2D-L, which differ by 13 amino acids at the N-terminus and have different signalling capabilities. These two isoforms are produced through differential splicing, but their regulati...
Autores principales: | Lai, C. Benjamin, Zhang, Ying, Rogers, Sally L., Mager, Dixie L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685100/ https://www.ncbi.nlm.nih.gov/pubmed/19304755 http://dx.doi.org/10.1093/nar/gkp174 |
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