Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

The envelope glycoprotein of human immunodeficiency virus (HIV) consists of an exterior glycoprotein (gp120) and a trans-membrane domain (gp41) and has an important role in viral entry into cells. HIV-1 entry has been validated as a clinically relevant anti-viral strategy for drug discovery. In the...

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Detalles Bibliográficos
Autores principales: Zhou, Jiehua, Swiderski, Piotr, Li, Haitang, Zhang, Jane, Neff, C. Preston, Akkina, Ramesh, Rossi, John J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685106/
https://www.ncbi.nlm.nih.gov/pubmed/19304999
http://dx.doi.org/10.1093/nar/gkp185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685106/
https://www.ncbi.nlm.nih.gov/pubmed/19304999
http://dx.doi.org/10.1093/nar/gkp185

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