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Regulation of Chk1

Chk1 is a serine/threonine protein kinase that is the effector of the G2 DNA damage checkpoint. Chk1 homologs have a highly conserved N-terminal kinase domain, and a less conserved C-terminal regulatory domain of ~200 residues. In response to a variety of genomic lesions, a number of proteins collab...

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Detalles Bibliográficos
Autores principales: Tapia-Alveal, Claudia, Calonge, Teresa M, O'Connell, Matthew J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685127/
https://www.ncbi.nlm.nih.gov/pubmed/19400965
http://dx.doi.org/10.1186/1747-1028-4-8