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Regulation of Chk1
Chk1 is a serine/threonine protein kinase that is the effector of the G2 DNA damage checkpoint. Chk1 homologs have a highly conserved N-terminal kinase domain, and a less conserved C-terminal regulatory domain of ~200 residues. In response to a variety of genomic lesions, a number of proteins collab...
Autores principales: | Tapia-Alveal, Claudia, Calonge, Teresa M, O'Connell, Matthew J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685127/ https://www.ncbi.nlm.nih.gov/pubmed/19400965 http://dx.doi.org/10.1186/1747-1028-4-8 |
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