Update on duloxetine for the management of stress urinary incontinence

Duloxetine is a relatively balanced serotonin and noradrenaline reuptake inhibitor (SNRI), which is the first drug with widely proven efficacy to have been licensed for the medical treatment of women with stress urinary incontinence (SUI). Despite favorable results from randomized controlled trials,...

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Detalles Bibliográficos
Autores principales: Basu, Maya, Duckett, Jonathan RA
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685222/
https://www.ncbi.nlm.nih.gov/pubmed/19503763
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author Basu, Maya
Duckett, Jonathan RA
author_facet Basu, Maya
Duckett, Jonathan RA
author_sort Basu, Maya
collection PubMed
description Duloxetine is a relatively balanced serotonin and noradrenaline reuptake inhibitor (SNRI), which is the first drug with widely proven efficacy to have been licensed for the medical treatment of women with stress urinary incontinence (SUI). Despite favorable results from randomized controlled trials, surgical management continues to be the mainstay of treatment for SUI. In this review we explore the pharmacology of duloxetine in the nervous system and lower urinary tract, and the evidence for its use in the management of women with urinary incontinence.
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spelling pubmed-26852222009-06-05 Update on duloxetine for the management of stress urinary incontinence Basu, Maya Duckett, Jonathan RA Clin Interv Aging Review Duloxetine is a relatively balanced serotonin and noradrenaline reuptake inhibitor (SNRI), which is the first drug with widely proven efficacy to have been licensed for the medical treatment of women with stress urinary incontinence (SUI). Despite favorable results from randomized controlled trials, surgical management continues to be the mainstay of treatment for SUI. In this review we explore the pharmacology of duloxetine in the nervous system and lower urinary tract, and the evidence for its use in the management of women with urinary incontinence. Dove Medical Press 2009 2009-05-14 /pmc/articles/PMC2685222/ /pubmed/19503763 Text en © 2009 Basu and Duckett, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Review
Basu, Maya
Duckett, Jonathan RA
Update on duloxetine for the management of stress urinary incontinence
title Update on duloxetine for the management of stress urinary incontinence
title_full Update on duloxetine for the management of stress urinary incontinence
title_fullStr Update on duloxetine for the management of stress urinary incontinence
title_full_unstemmed Update on duloxetine for the management of stress urinary incontinence
title_short Update on duloxetine for the management of stress urinary incontinence
title_sort update on duloxetine for the management of stress urinary incontinence
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685222/
https://www.ncbi.nlm.nih.gov/pubmed/19503763
work_keys_str_mv AT basumaya updateonduloxetineforthemanagementofstressurinaryincontinence
AT duckettjonathanra updateonduloxetineforthemanagementofstressurinaryincontinence

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