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The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly
After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from an...
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Formato: | Texto |
Lenguaje: | English |
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Dove Medical Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685240/ https://www.ncbi.nlm.nih.gov/pubmed/19503781 |
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author | Ulahannan, Danny Wagg, Adrian |
author_facet | Ulahannan, Danny Wagg, Adrian |
author_sort | Ulahannan, Danny |
collection | PubMed |
description | After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies. |
format | Text |
id | pubmed-2685240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-26852402009-06-05 The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly Ulahannan, Danny Wagg, Adrian Clin Interv Aging Review After lifestyle and behavioral measures to control overactive bladder, the mainstay of pharmacological treatment is the use of antimuscarinic therapy. Overactive bladder predominantly affects older people, who experience the most severe disease, and are also at a greater risk of side effects from antimuscarinic therapy. Thus it is imperative that data are available on the efficacy and tolerability of this group of drugs when used in older people. This article reviews the pathophysiology of the condition, its effect on the elderly and the evidence for the use of extended release tolterodine in the elderly using data from placebo and active drug controlled studies. Dove Medical Press 2009 2009-05-14 /pmc/articles/PMC2685240/ /pubmed/19503781 Text en © 2009 Ulahannan and Wagg, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Review Ulahannan, Danny Wagg, Adrian The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_full | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_fullStr | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_full_unstemmed | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_short | The safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
title_sort | safety and efficacy of tolterodine extended release in the treatment of overactive bladder in the elderly |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685240/ https://www.ncbi.nlm.nih.gov/pubmed/19503781 |
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