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The p53HMM algorithm: using profile hidden markov models to detect p53-responsive genes
BACKGROUND: A computational method (called p53HMM) is presented that utilizes Profile Hidden Markov Models (PHMMs) to estimate the relative binding affinities of putative p53 response elements (REs), both p53 single-sites and cluster-sites. These models incorporate a novel "Corresponded Baum-We...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685388/ https://www.ncbi.nlm.nih.gov/pubmed/19379484 http://dx.doi.org/10.1186/1471-2105-10-111 |