Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture

Replication has become the gold standard for assessing statistical results from genome-wide association studies. Unfortunately this replication requirement may cause real genetic effects to be missed. A real result can fail to replicate for numerous reasons including inadequate sample size or variab...

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Detalles Bibliográficos
Autores principales: Greene, Casey S., Penrod, Nadia M., Williams, Scott M., Moore, Jason H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685469/
https://www.ncbi.nlm.nih.gov/pubmed/19503614
http://dx.doi.org/10.1371/journal.pone.0005639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685469/
https://www.ncbi.nlm.nih.gov/pubmed/19503614
http://dx.doi.org/10.1371/journal.pone.0005639

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