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Failure to Replicate a Genetic Association May Provide Important Clues About Genetic Architecture
Replication has become the gold standard for assessing statistical results from genome-wide association studies. Unfortunately this replication requirement may cause real genetic effects to be missed. A real result can fail to replicate for numerous reasons including inadequate sample size or variab...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685469/ https://www.ncbi.nlm.nih.gov/pubmed/19503614 http://dx.doi.org/10.1371/journal.pone.0005639 |