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Stable Vascular Connections and Remodeling Require Full Expression of VE-Cadherin in Zebrafish Embryos

BACKGROUND: VE-cadherin is an endothelial specific, transmembrane protein, that clusters at adherens junctions where it promotes homotypic cell-cell adhesion. VE-cadherin null mutation in the mouse results in early fetal lethality due to altered vascular development. However, the mechanism of action...

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Detalles Bibliográficos
Autores principales: Montero-Balaguer, Mercedes, Swirsding, Kendra, Orsenigo, Fabrizio, Cotelli, Franco, Mione, Marina, Dejana, Elisabetta
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685470/
https://www.ncbi.nlm.nih.gov/pubmed/19503615
http://dx.doi.org/10.1371/journal.pone.0005772